Custom RNA Synthesis and Purification

IDT has the expertise to deliver custom-synthesized RNA with the yield and purity that today's researcher demands. RNA is shipped deprotected and desalted in 2-3 business days or deprotected and purified in 4-6 business days. Please inquire for turnaround on 5 µmole and 10 µmole RNA synthesis.  RNA oligos are provided with sodium as the counter-ion.

*Price per base, unless otherwise noted.  NO SETUP FEES!

Available Lengths: RNA oligos are available from 10 - 50 bases for 100 nmole, and 5 - 50 bases for 250 nmole, 1 µmole, 5 µmole and 10 µmole.

2'-O-methyl RNA

2'-O-methyl RNA is a useful RNA analog that is resistant to degradation by single-stranded ribonucleases.

Large-Scale RNA Synthesis

RNA, RNA analogs and chimeras are available in quantities up to ten grams.  IDT continues the tradition of providing researchers with the highest quality RNA oligonucleotide synthesis, in quantities ranging from multi-mg to several grams.

Custom Services:

• Target validation and development programs for siRNA, DsiRNA, aptamers, ribozumes, antisense and others
• Extensive QC packages tailored to researchers needs
• Sterile-filtered oligo preparations available, endotoxin free
• Harmonized protocols allow simple transfer to our kilo-scale cGMP manufacturing partner
• Contact Customer Service for more information

Technical Note:

Generally for RNA oligos, 1 OD260 ≈ 100/x nanomoles, where x is the length of the oligos in bases.  For the average 20-mer RNA oligo, 1 OD = 5 nmoles.  Actual nanomoles per OD varies with sequence composition.

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