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Does IDT allow base modifications with their gene products?

IDT requires both strands of Genes and MiniGenes products to be 100% complementary. Therefore, mixed bases and modifications are not available for this product type—Genes and MiniGenes sequences may only be composed of A/C/G/T bases. Genes and MiniGenes products are delivered double-stranded in a vector. Ultramer™ Oligonucleotides, which allow mixed bases, can be used for gene synthesis if your method allows.