Cited
Scientific Publications Referencing IDT Products


Advantageous Properties of Dicer-Substrate Interfering RNA (DsiRNA) Enable Improved RNAi-Based Gene Silencing

Comparison of cononical siRNA design to DsiRNAs for performance in siRNA processing and RISC assembly, leading to stronger silencing efficacy.

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Double-Quenched Probes Increase Sensitivity of qPCR Assay Detecting Viral Load

Use of a ZEN™ Double-Quenched Probe results in a marked decrease in background fluorescence compared to an identical TaqMan® probe containing only a single quencher. The data suggest that such double-quenched probes may be a better approach for other qPCR probe-based assays.

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Decoding Cas9 Orthologs Using gBlocks® Gene Fragments

gBlocks Gene Fragments were used to create Cas9 orthologs as well as tracRNA expression cassettes for each ortholog tested.

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Nanoparticle Delivery of TNF-α targeting DsiRNA as Treatment for Rheumatoid Arthritis

DsiRNA-loaded PLGA nanoparticles mediate dose-dependent silencing of TNF-α in vitro.

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A Fast, Sensitive, Cost-Effective Alternative to Radiolabeling and HPLC/MS for Measuring dNTPs

A rapid and sensitive fluorescence-based method that uses synthetic templates (IDT oligonucleotides), a PrimeTime® Primer, and ZEN™ Double-Quenched Probes for quantifying cellular dNTPs.

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Caffeine Addicted Bacteria

Use of IDT gBlocks® Gene Fragments in Gibson Isothermal Assembly™ reactions to generate some of the plasmid constructs in this work.

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Barcoding Living Cell Populations with Zinc-Finger DNA-Binding Domains

IDT gBlocks® Gene Fragments were used to generate surface zinc-finger DNA-binding domains for barcoding distinct cell lines. These live cells could then be tracked within a heterogeneous mix of cells.

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Mutagenesis Using gBlocks® Gene Fragments

Just 3 synthetic, high fidelity, double-stranded gBlocks™ Gene Fragments used to mutate 18 different sites over the entire exon 7, 1039 bp sequence.

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Quick Oligonucleotide Assembly

A protocol for assembling high-fidelity Ultramer™ oligonucleotides with overlapping sequences into large constructs using Saccharomyces cerevisiae.

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Efficient Multiplex Processing of Pooled Barcoded Samples

Authors describe a cost-effective procedure for parallel genomic library preparation from multiple samples followed by targeted enrichment of pooled barcoded samples. The protocol is compatible with microarray- and solution-based capture methods.

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