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Special, Online Only Articles from IDT

iGEM, and the vision for the next generation of synthetic biology researchers

Randy Rettberg, Co-founder and President of iGEM, discusses the 2016 iGEM competition in this video interview. Learn about his vision for the future for the students that participate in iGEM, as well as the future of synthetic biology.

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Improving gene expression experiments with PrimeTime® Gene Expression Master Mix

Watch this recorded webinar to learn about the benefits of our PrimeTime® Gene Expression Master Mix for qPCR experiments. The presentation covers singleplex and multiplex experiments, online tools for planning qPCR experiments, and a discussion of the excellent thermal stability of the master mix.

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Strategies for optimizing high throughput qPCR for expression profiling

Webinar summary: Learn how to address the challenges of high throughput RT-qPCR expression profiling from a prominent qPCR expert, Dr. Mikael Kubista (TATAA Biocenter, Sweden).

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Webinar: Alt-R™ CRISPR-Cas9 System ribonucleoprotein delivery optimization

Webinar: Genome editing using a Cas9:tracrRNA:crRNA ribonucleoprotein (RNP) provides excellent editing efficiency, while reducing off-target editing and cell death. Watch this recorded presentation to find out how to easily generate and deliver CRISPR RNAs and Cas9 nuclease in an RNP format, using the optimized Alt-R™ CRISPR-Cas9 System.

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DNA Day: Celebrating the Impact of Our Genomics Research on Society and Looking Toward the Future

What will be the impact of genomics on our science and society on the 100th year anniversary of Crick and Watson’s discovery? Read the winning entries of our 2015 DNA Day essay contest that asked researchers to describe their predictions for the impact of genomics in 2053.

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IDT ISO 14001 Sustainability Award Enabling Discovery in Biodiversity

Read about the first IDT Sustainability Award—Enabling Discovery in Biodiversity. Held in 2015, the regional contest was open to all academic researchers in Southern California. The winner, Dr Patricia Tavormina, received $14001 of Oligo Credit from IDT. For 2015, the award will focus on biodiversity. Future awards may focus on other geographic regions and other areas of study. www.idtdna.com/sustainability

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CRISPR + Gibson Assembly® approach addresses cloning limitations

Citation summary: A method for combining CRISPR/Cas9 genome editing and the Gibson Assembly® Method to seamlessly assemble large DNA constructs.

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Melt curve analysis for improved intercalating dye qPCR

Listen to this discussion of the benefits and limitations of melt-curve analysis using clear example—presented as a webinar. Read how PrimeTime Predesigned qPCR Primer Assays are designed to be compatible with intercalating dyes, and can also be transitioned to probe-based assays.

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Product Spotlight: Advantages of high quality, probe-based gene capture panels

Target enrichment by hybrid capture lets you focus your genomic analysis on specific regions of interest, increasing depth of coverage of targeted sequences and improving the detection of rare genomic events. You can create custom human gene capture panels quickly and cost-effectively using IDT preconfigured pools of probes targeting the coding sequences (CDS) of human protein-coding genes, or with predesigned disease or exome panels.

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CRISPR Genome Modification: Getting Started

Learn how CRISPR/Cas9 can be used for genome modification and get connected to the CRISPR resources available on our website.

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Augmenting pathology data with molecular profiling for improved cancer treatment

Foundation Medicine uses a unique approach to targeted next-generation sequencing to generate molecular information that will better inform cancer categorization and treatment decisions. Review this summary and view the presentation given at the 2014 Association for Molecular Pathology Annual Meeting (AMP) by Dr Geoff Otto (Foundation Medicine).

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Get just the targets you need in NGS capture panels

There are several disadvantages to purchasing fixed target capture panels or having custom panels manufactured. A solution is to create your own custom NGS target capture panels from stocked human gene probe pools.

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Improving uniform coverage of targeted sequences for NGS

Learn about the challenges researchers face for obtaining uniform coverage of NGS data and how IDT xGen® Lockdown® Probes are uniquely positioned to facilitate uniform sequence coverage.

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The gene construction revolution

See how use of high-quality, custom dsDNA fragments as a starting material allows you to turn what might otherwise be multi-step cloning assemblies into simpler reactions.You can often just order the entire target sequence ready for cloning or other uses.

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How important are those NGS metrics?

Of the many metrics used in evaluating target capture data for NGS applications,read what our researchers consider important for evaluating performance of target enrichment panels.

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You want a unicorn with your oligos? Umm, yeah we can do that!

Injecting a little fantasy into your biological reality.

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