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Core Concepts
Scientific Fundamentals Explained

Unraveling RNA – The Importance of a 2' Hydroxyl

On paper, the small structural differences between RNA and DNA may not look substantial but, in practice, these small differences have major significance for the biological role of RNA.

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Modification Highlight: Cholesterol-TEG

Cholesterol-TEG is available from IDT for both DNA and RNA oligos on scales from 100 nmole to 10 μmole. Because cholesterol is difficult to manufacture, it requires HPLC purification. To order, select Cholesterol-TEG from the modifications tab on the oligo order page.

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