xGen Lockdown Probes are individually synthesized 5′-biotinylated oligos for hybridization capture enrichment in next generation sequencing. xGen Lockdown Probes are produced using the same industry-leading, high-fidelity synthesis chemistry developed for Ultramer® Oligonucleotides.
These probes can be used for creating custom capture panels that can be optimized, expanded, and combined with other panels. xGen Lockdown Probes can also be used to enhance the performance of existing capture panels, rescuing poorly represented regions such as areas of high GC content.
With xGen Lockdown Probes, you can:
- Design probes for any sequence in any species using your specified parameters for target definition, probe length, and
- Use for human probe targets when xGen Predesigned Gene Capture Pools do not match your criteria for design
- Transition to high volume applications easily with 3 production scales
- Use gene symbols, gene IDs, and BED files to identify human, mouse, and rat gene targets; the tools also accepts RefSeq
accession numbers or FASTA-formatted sequences