xGen® Human ID Research Panel

The xGen Human ID Research Panel enables unique identification of individual samples from a larger population. The panel provides genomic target enrichment of a distinctive set of single nucleotide polymorphisms (SNPs), including high minor allele frequency SNPs and a set of 5 gender marker SNPs. The Human ID Research Panel has a power of discrimination greater than 1 in 5 million, and is compatible with various sample types, including cell-free DNA and DNA from formalin-fixed, paraffin-embedded (FFPE) tissues.

  • Ensure correct sample identity in NGS studies
  • Use as a spike-in or standalone panel with unique, modular format
  • Consistently achieve superior results with individually synthesized and quality controlled probes manufactured to GMP standards

xGen® Human ID Research Panel

Validated spike-in panel designed to capture 76 distinct, highly polymorphic sites across the human genome for unique identification of any human sample.

ProductPricing
xGen® Human ID Research Panel v1.0, 16 rxn$350.00 USD
xGen® Human ID Research Panel v1.0, 96 rxn$950.00 USD

The xGen® Human ID Research Panel provides genomic target enrichment for a definitive set of single nucleotide polymorphisms (SNPs) selected to identify a unique individual from a population of over 5 million biological samples. The panel has been tested with DNA from formalin-fixed, paraffin-embedded (FFPE) tissues, cell-free DNA (cfDNA), and other sample types.

This panel captures 76 distinct, highly polymorphic sites using 229 individually synthesized xGen Lockdown® Probes. The xGen Human ID Research Panel can be combined with any xGen Lockdown Panel or custom xGen Lockdown Probe set. When spiked into another target capture panel, the xGen Human ID Research Panel provides high on-target performance and coverage uniformity. Panels of various sizes have demonstrated no compromise of data with the addition of this panel. The Human ID Research Panel can also be run as a standalone* panel to confirm sample identity before performing larger, more expensive sequencing studies.

Use the xGen Human ID Research Panel to:

  • Identify tumor/normal paired samples
  • Track and manage individual samples during longitudinal studies
  • Detect sample misidentification

Unlike other target capture reagents, xGen Lockdown Probes are individually column-synthesized, and then quality controlled by ESI mass spectrometry. Additionally, predesigned xGen Lockdown Panels are functionally validated to ensure consistent and reliable results. This extra attention to quality delivers high on-target performance and coverage uniformity.

xGen Lockdown Panels and Probes for diagnostic purposes are also available. Contact GMPinfo@idtdna.com for more information.



* The xGen Human ID Research Panel contains a relatively small number of probes. When used as a standalone panel, expect lower on-target capture results than when used as a spike in to a larger panel. This reduced performance is typical of small panels in hybridization capture enrichment.