N6-methyladenosine (m6A)—modulating RNA localization, structure, stability, splicing, and translation

Modification Highlight: Read about the mechanism of methylation and functions of N6-methyladenosine (m6A) modifications in the cell. N6-methyladenosine is available as a popular non-catalog modification from IDT, providing a substrate for studying the role of this natural, reversible, post-translational modification.

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Valuable support for genomics research

Product Spotlight: Take advantage of the full list of products, services, and support IDT provides for genomics research. Whether you are performing sequencing, gene expression, genome editing, or synthetic biology experiments, IDT has cost-effective, rapid, high quality, and high throughput solutions.

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Insert an abasic site into your sequence

Use the dSpacer, rSpacer, and Abasic II modifications to introduce abasic sites into DNA or RNA oligonucleotides. These modifications create a single base space that replicates the loss of base pairing ability by a nucleotide.

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Need a library of related DNA or RNA oligo sequences?

Build variability into your oligo sequences by incorporating Mixed Bases. We offer mixes of multiple base types as well as nonstandard and modified bases.

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Increase the Tm of short, AT-rich primers and probes

Modification highlight: Add this modified base to increase the melting temperature (Tm) of primers and probes. It is especially useful when you need to work with short A-T rich sequences.

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