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TECHVAULT > FAQ > PRODUCT SUPPORT

What is your standard desalting procedure? What additional purification options do I have?

IDT uses a proprietary desalting technique which has been shown to remove the same short truncation products and small organic contaminants from the prep as an OPC method, such as MWG's HSPF method would.

If your main concern are the n-1 mers produced during the synthesis, the only way to effectively remove them is to use either PAGE or HPLC. PAGE is strongly recommended for longer unmodified oligos, while HPLC is the preferred method for oligos with either fluorescent dyes or attachment modifications.

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