Top Questions

How does the efficiency of RNA synthesis compare with DNA?

RNA synthesis is slightly over 98% efficient, while DNA couples at roughly 99.2%. As with DNA, short RNA oligos will include a low percentage of truncated products as a result of the less than 100% efficiency of coupling. These oligos may be sufficiently pure for your application without requiring additional purification. For sensitive RNA applications, such as silencing, we strongly recommend purification.
  • rna
  • coupling
Product Support Topics