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What are AMOs (miRNA inhibitors) and how are they used?

Anti-microRNA Oligonucleotides (AMOs), or microRNA inhibitors, are steric blocking antisense reagents that inhibit microRNA (miRNA) function by hybridizing to and repressing the activity of a mature miRNA. The miRNA regulatory networks exert some level of control in the majority of cellular biological processes, including cell differentiation, apoptosis, and proliferation. AMOs/microRNA inhibitors can be used to inhibit miRNA function, both to investigate that function and for therapeutic purposes to correct diseases associated with miRNA dysregulation. You can read more about as well as order IDT® miRNA Inhibitors at miRNA Inhibitor product page.
Tags:
  • mirna
  • microrna
  • inhibitor
  • Anti-miRNA
  • AMO
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