RNAi—Immune Effects


This bibliography contains a list of research papers published by IDT scientists (bold). Click on the reference to read the PubMed abstract, or entire paper, if published in an open access journal. Otherwise, you will be able to obtain a PDF download of the paper through the PubMed site.

  1. Sarvestani ST, Tate MD, Moffat, JM, Jacobi AM, Behlke, MA, Miller AR, Beckham SA, McCoy CE, Chen W, Mintern JD, O’Keeffe M, John M, Williams BR, Gantier MP. (2014) Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8. J Virol, 88(2):799–810.
  2. Gantier MP, Irving AT, Kaparakis-Liaskos M, Xu D, Evans VA, Cameron PU, Bourne JA, Ferrero RL, John M, Behlke MA, Williams BR. (2010) Genetic modulation of TLR8 response following bacterial phagocytosis. Hum Mutat, 31(19):1069–1079.
  3. Gantier MP, Tong S, Behlke MA, Irving AT, Lappas M, Nilsson UW, Latz E, McMillan NA, Williams BR. (2010) Rational design of immunostimulatory siRNAs. Mol Ther, 18(4):785–795.
  4. Gantier MP, Tong S, Behlke MA, Xu D, Phipps S, Foster PS, Williams BR. (2008) TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages. J Immunol, 180(4):2117–2124.
  5. Zamanian-Daryoush M, Marques JT, Gantier MP, Behlke MA, John M, Rayman P, Finke J, Williams BR. (2008) Determinants of cytokine induction by small interfering RNA in human peripheral blood mononuclear cells . J Interferon Cytokine Res, 28(4):221–233.
  6. Marques JT, Devosse T, Wang D, Zamanian-Daryoush M, Serbinowski P, Hartmann R, Fujita T, Behlke MA, Williams BRG. (2006) A structural basis of discriminating between self and nonself double-stranded RNAs in mammalian cells. Nat Biotechnol, 24:559–565.
  7. Robbins MA, Li M, Leung I, Li H, Boyer DV, Song Y, Behlke MA, Rossi JJ. (2006) Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro . Nat Biotechnol, 24(5):566–571.