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3' 5-Methyl dC

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5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.

Scientific Details
MW:303.2
Mod Code:/3Me-dC/
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo $65.00 USD Add To Order
250 nmole DNA Oligo $80.00 USD Add To Order
1 umole DNA Oligo $120.00 USD Add To Order
5 umole DNA Oligo $240.00 USD Add To Order
10 umole DNA Oligo $475.00 USD Add To Order
100 nmole RNA Oligo $65.00 USD Add To Order
250 nmole RNA Oligo $80.00 USD Add To Order
1 umole RNA Oligo $120.00 USD Add To Order
5 umole RNA Oligo $240.00 USD Add To Order
10 umole RNA Oligo $475.00 USD Add To Order
Structure
Structure

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