Your Questions For Our Resident Expert
How do I order an oligonucleotide with a modification?
When ordering, select the Custom DNA Oligos option, and then the type of oligo product you desire. At the bottom of that ordering page you will see tabs that read 5’ Mods, Internal Mods, and 3’ Mods. Most modifications are not available on the 25 nmole scale, so if you do not see the modification you are looking for, increase your synthesis scale to at least 100 nmol. This will increase the menu of modification options available. When you find the modification you want, click on the “Add” button on the left, which will add the appropriate code to your sequence.