IDT publications

Peer-reviewed articles published by IDT scientists. Filter using one or more categories to focus on specific topics.

159 Citations found

Dahan L, Huang L, Kedmi R, Behlke MA, and Peer D. (2013) SNP detection in mRNA in living cells using allele specific FRET probes. PLoS ONE, 8 : e72389.
Tetreault P, Beaudet N, Perron A, Belleville K, Rene A, Cavelier F, Martinez J, Stroh T, Jacobi AM, Rose SD, Behlke MA, and Sarret P. (2013) Spinal NTS2 receptor activation reverses signs of neuropathic pain. FASEB J, 27 : 3741-3752.
Fernandez G, Zaikos TD, Khan SZ, Jacobi AM, Behlke MA, Zeichner SL. (2013) Targeting Iκβ proteins for HIV latency activation: the role of individual Iκβ and NF-κβ proteins. J Virol, 87 : 3966–3978.
Ramachandran S, Karp PH, Jiang P, Ostedgaard LS, Walz AE, Fisher JT, Keshavjee S, Lennox KA, Jacobi AM, Rose SD, Behlke MA, Welsh MJ, Xing Y, McCray PB Jr. (2012) A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proc Natl Acad Sci USA, 109 : 13362–13367.
Gantier MP, Stunden HJ, McCoy CE, Behlke MA, et al. (2012) A miR-19 regulon that controls NF-kB signaling. Nucleic Acids Res, 40 : 8048–8058.
Janas MM, Wang B, Harris AS, Aguiar M, Shaffer JM, Subrahmanyam YV, Behlke MA, Wucherpfennig KW, Gygi SP, Gagnon E, Novina CD. (2012) Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins. RNA, 18 : 2041–2055.
Zhou J, Song M-S, Jacobi AM, Behlke MA, Wu X, Rossi JJ. (2012) Deep sequencing analyses of DsiRNAs reveal the influence of 3’ terminal overhangs on dicing polarity, strand selectivity and RNA editing of siRNAs. Mol Therapy Nucleic Acids, 1 : e17.
Hernandez FJ, Stockdale KR, Huang L, Horswill AR, Behlke MA, McNamara JO. (2012) Degradation of nuclease-stabilized RNA oligonucleotides in mycoplasma-contaminated cell culture media. Nucleic Acid Ther, 22 : 58–68.
Krishnamurthy S, Behlke MA, Ramachandran S, Salem AK,McCray PB Jr, Davidson BL. (2012) Manipulation of cell physiology enables gene silencing in well-differentiated airway epithelia. Mol Ther Nucl Acids, 1 : e41.
Munoz-Alarcon A, Guterstam P, Romero C, Behlke MA, Lennox KA, Wengel J, El Andaloussi S, Langel U. (2012) Modulating anti-microRNA-21 activity and specificity using oligonucleotide derivatives and length optimization. ISRN Pharm, 2012 : e407154.
Kredo-Russo S, Mandelbaum AD, Ness A, Alon I, Lennox KA, Behlke MA, Hornstein E. (2012) Pancreas-enriched miRNA refines endocrine cell differentiation. Development, 139 : 3021–3031.
Rettig GR, Behlke MA. (2012) Progress towards in vivo use of siRNAs - II. Mol Ther, 20 : 483–512.
Lundberg P, Yang H-J, Jung S-J, Behlke MA, Rose SD, Cantin EM. (2012) Protection against TNFα-dependent liver toxicity by intraperitoneal liposome delivered DsiRNA targeting TNFα in vivo. J Control Release, 160 : 194-199.
Thiel WH, Bair T, Peek AS, Liu X, Dassie J, Stockdale KR, Behlke MA, Miller FJ, Giangrande PH. . (2012) Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection. PLoS One, 7 : e43836.
Dallas A, Ge Q, Ilves H, Kumar P, Shorenstein J, Kazakov SA, Cuellar TL, McManus MT, Behlke MA, Johnston BH. (2012) Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing. Nucleic Acids Res, 40 : 9255–9271.
Huang YZ, Hernandez FJ, Gu B, Stockdale KR, Nanapaneni K, Scheetz TE, Behlke MA, Peek AS, Bair T, Giangrande PH, McNamara JO.. (2012) RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. Mol Pharmacol, 82 : 623–635.
Weinstein S, Emmanuel R, Jacobi AM, Abraham A, Behlke MA, Sprague AG, Novobrantseva T, Nagler, A, Peer D. (2012) RNA inhibition highlights Cyclin D1 as a potential therapeutic target for Mantle Cell Lymphoma. PLoS ONE, 7 : e43343.
Khairuddin N, Gantier MP, Blake SJ, Wu SY, Behlke MA, Williams BR, McMillan NA. (2012) SiRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo. Immunol Cell Biol, 90 : 187–196.
Kim N, Jiang D, Jacobi AM, Lennox KA, Rose SD, Behlke MA, Salem AK. (2012) Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA. Int J Pharm, 427 : 123–133.
Rose S, Behlke MD. (2012) Synthetic dicer-Substrate siRNAs as triggers of RNA interference. In: RNA Interference from Biology to Therapeutics, 1 : 31–56.
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