All xGen blocking oligos are compatible with any xGen Lockdown® Panel or custom xGen Lockdown Probe set. Each oligo is individually synthesized and assessed by mass spectrometry for quality control.
xGen Universal Blockers
IDT offers two different ready-to-use, universal blocker reagents. xGen Universal Blockers—TS Mix blocks Illumina LT (p5,
p7 – 6 nt and 8 nt) and HT (i5, i7) adapters and is compatible with ligation-based library prep protocols, such as Illumina
TruSeq kits. xGen Universal Blockers—NXT Mix contains adapter blockers that are optimized for use with Illumina Nextera
library prep kits.
xGen Universal Blockers are offered in 16- and 96-reaction formats for convenient experiment design and use with xGen Lockdown
Panels or xGen Lockdown Probe sets.
Custom xGen Blocking Oligos
Custom blocking oligos can be ordered for specialized applications or other sequencing platforms, and are offered
with specified modifications. While we have identified the most commonly used modifications and services required for
effective blocking in next generation sequencing, we understand that certain modifications or services may improve the
performance of blocking oligo performance for your specific application.
For more information about available blockers, please contact our customer care team at email@example.com.