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Are you able to synthesize DNA oligos containing deoxyuridine (dU) instead of (deoxythymidine) dT?
We routinely make oligos that include deoxyuridine in place of deoxythymidine bases. The minimum synthesis scale for oligos containing dU is 100 nmoles. The modification code for internal deoxyuridine in a sequence is /ideoxyU/, while 5’ and 3’ incorporation have the modification codes of /5deoxyU/ and /3deoxyU/, respectively. More details, including pricing information, are provided on the Modifications page under the Products tab at www.idtdna.com.