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Do you offer universal bases?
IDT offers the universal bases 5' nitroindole and deoxyInosine, which are sometimes used as universal bases. 5' Nitroindole does not favor any particular base-pairing but does contribute to duplex stability. DeoxyInosine has some base-pairing bias but is less destabilizing than mismatches involving the four standard bases. For more information, see the article, DeoxyInosine: Don’t Call Me a Universal Base!