Processing
Frequently asked questions
Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.
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How does the efficiency of RNA synthesis compare with DNA?
RNA synthesis tends to have a lower coupling efficiency than DNA synthesis. As with DNA, short RNA oligos will include a low percentage of truncated products as a result of the less than 100% efficiency of coupling. These oligos may be sufficiently pure for your application without requiring additional purification.
For RNA applications that require high-precision, such as silencing or CRISPR mediated genome editing, we strongly recommend purification.