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Frequently asked questions

Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.

Is it possible to order an oligo with both an amino modifier modification and a modification attached via NHS Ester chemistry?

Unfortunately, we are not able to provide oligos with both a free amine and an NHS ester modification. The NHS ester will bind to any free amino group as it is attached to the oligo post synthesis.

IDT recommends using a modification that is attached via a different chemistry, such as Click chemistry or phosphoramidite chemistry.

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Custom DNA & RNA

*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.