This is a difficult question to answer. However, because the frequency of the dinucleotide “GG” is 5.21% in the human genome , it is reasonable to expect that most genes will contain at least the PAM sequence (NGG) of the S. pyogenes Cas9.
*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.