Due to recognition of cytosolic dsDNA by innate immune response pathways, careful consideration of the final Alt-R™ HDR Donor Block concentration is necessary to avoid cytotoxicity. We recommend testing for optimal concentrations for each cell line you use, as sensitivity to dsDNA may vary. To learn more, go to the Alt-R Donor Blocks protocol.
*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.