TECHVAULT > FAQ > APPLICATION SUPPORT > ANTISENSE OLIGOS

I get an error message when ordering my thioate oligo online, can you help?

The asterisk included in the antisense sequences actually denotes a phosphorothioate linkage and should be placed between the two bases you would like to have linked with a phosphorothioate bond. These bonds can only be located on a Phos linkage and since our oligos have OH ends, thioate bonds can not be placed on the absolute 3' or 5' end of your oligo.

For example, you would need to enter a sequence like this: N*N*N*NNNNN*N*N*N

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