I need an oligo with a high level of purity. What purification method should I choose?
For an oligo that is unmodified and needs to have a high level of purity we recommend PAGE purification. With most unmodified oligos of up to 60 bases, PAGE purification routinely achieves 85% full length product. For modified oligos up to 50 bases we recommend HPLC, while we recommend IE HPLC for those that are longer.