How do I order a phosphorothioate modified oligo?

Jul 25, 2013, 20:21 PM
IDT uses a simple notation for phosphorothioate bonds (PS bonds).  Insert an asterisk (*) between the bases within your sequence to denote a phosphorothioate chemical modification.  The following example has a PS bond between the T and G bases:  5’- TTTTTT*GGGGGG -3’.  PS bonds introduced between the last nucleotides at the 5'- or 3'-end of the oligo inhibit exonuclease degradation. Order PS-modified oligos at:
  • Ordering
  • phosphorothioate
  • exonuclease