Additionally, NGS library preparation workflows can be cumbersome, allowing many points for manual errors. Bioinformatic pipelines can be expensive and time-consuming to maintain. A pipeline may also lack the QC and statistical tools necessary to reduce
errors and guide calling, which can leave it to lab staff to make difficult calls.
Archer NGS assay solutions for solid tumor research resolves these concerns with patented AMP™ chemistry, streamlined parallel workflows, and user-friendly analysis. Additionally, assays are designed to fit your lab’s unique needs from comprehensive
profiling and high-throughput workflows, to smaller footprint assays and low-throughput manual workflows.
Detect more with AMP chemistry
Anchored Multiplex PCR (AMP) is a target enrichment method that uses molecular barcoded adapters and single, nested, gene-specific primers for amplification, permitting open-ended capture of DNA, RNA, and cfDNA fragments. This approach enables the detection of novel fusions (Figure
2), allows for flexible primer design, and protects against dropout of primers. MBC adapter ligation prior to PCR combined with Archer Analysis software power the correction of systematic errors and quantitative analysis of the original unamplified template.