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3' deoxyInosine

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Historically, the first universal base employed was 2’-deoxyInosine (dI). DeoxyInosine is a naturally occurring base that, while not truly universal, is less destabilizing than mismatches involving the four standard bases. Hydrogen bond interactions between dI and dA, dG, dC and dT are weak and unequal, with the result that some base-pairing bias does exist with dI:dC > dI:dA > dI:dG > dI:dT. When present in a DNA template, deoxyInosine preferentially directs incorporation of dC in the growing nascent strand by DNA polymerase.

Scientific Details
Mod Code:/3deoxyI/
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo $10.00 USD Add To Order
250 nmole DNA Oligo $12.00 USD Add To Order
1 umole DNA Oligo $18.00 USD Add To Order
5 umole DNA Oligo $37.50 USD Add To Order
10 umole DNA Oligo $75.00 USD Add To Order
100 nmole RNA Oligo $10.00 USD Add To Order
250 nmole RNA Oligo $12.00 USD Add To Order
1 umole RNA Oligo $18.00 USD Add To Order
5 umole RNA Oligo $37.50 USD Add To Order
10 umole RNA Oligo $75.00 USD Add To Order
Structure
Structure

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