Cholesterol can be conjugated to oligonucleotides and can facilitate uptake into cells. It has been used as a transfection aid for antisense oligos and siRNAs, both in vitro and in vivo. Cholesterol is a very hydrophobic modification that is best purified using RP-HPLC.

Scientific Details

MW:	756
Mod Code:	/3CholTEG/

Pricing Details

Product	Pricing	Order
100 nmole DNA Oligo	$103.00 USD	Add To Order
250 nmole DNA Oligo	$103.00 USD	Add To Order
1 umole DNA Oligo	$305.00 USD	Add To Order
2 µmole DNA Oligo	$404.00 USD	Add To Order
100 nmole RNA Oligo	$103.00 USD	Add To Order
250 nmole RNA Oligo	$103.00 USD	Add To Order
1 umole RNA Oligo	$305.00 USD	Add To Order
* Requires HPLC Purification

Structure

Purification Compatibility

Requires HPLC	Yes
Requires IE-HPLC	No
Allows PAGE	No
Requires RNase-Free HPLC	No